6-Maleimidohexanoic Acid CAS 55750-53-3

We can provide 6-Maleimidohexanoic acid CAS 55750-53-3 with a certificate of analysis (COA), method of analysis (MOA), route of synthesis (ROS), and material safety data sheet (MSDS)

 

Chemical Properties：

Density:1.3±0.1 g/cm3

Index of Refraction:1.537

Boiling point: 407.3±28.0 °C at 760 mmHg

Flash Point:200.1±24.0 °C

 

Synonyms：

6-maleimidocaproic acid

6-Maleimidohexanoic acid

N-(5-CARBOXYPENTYL)MALEIMIDE

N-MALEOYL-6-AMINO-CAPROIC ACID

N-EPSILON-MALEIMIDOCAPROIC ACID

N-(5-Carboxy-n-pentyl)MaleiMide

2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic Acid

6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid

6-Maleimidocaproic acid, N-(5-Carboxypentyl)maleimide, N-Maleoyl-6-aminocaproic acid

6-Maleimidohexanoic acid,6-Maleimidocaproic acid, N-(5-Carboxypentyl)maleimide, N-Maleoyl-6-aminocaproic acid

 

Uses:

6-Maleimidohexanoic acid CAS 55750-53-3 has a variety of applications in biochemical research and protein chemistry:

- As a cross-linking reagent: The maleimide group of N-maleimidohexanoic acid binds to proteins or peptides containing sulfhydryl groups to form a cross-linking product, which can be used to study protein structure and function.

- Can be used as a probe:N-Maleimidohexanoic acid can bind to compounds or proteins containing amino groups for tracing, labeling, or detection of specific biomolecules.

Method of Preparation:

6-Maleimidohexanoic acid CAS 55750-53-3 is generally prepared by the following steps:

1. maleic anhydride is reacted with hexanoyl chloride to produce maleone propionyl chloride.

2. maleone propionyl chloride is then reacted with L-leucine to produce N-maleimidohexanoic acid.

 

Safety Information:

- N-Maleimidohexanoic acid may be irritating to the eyes, skin, and respiratory system and contact should be avoided.

- Appropriate personal protective equipment such as gloves, protective eyewear and protective masks should be worn during use.

- It should be stored in a dry, ventilated area away from sources of ignition and oxidizing agents.

- In case of accidental ingestion or inhalation, seek immediate medical attention.

 

 

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