
2-Bromo-6-methylquinoline CAS 302939-86-2
What is 2-Bromo-6-methylquinoline CAS 302939-86-2?
2-Bromo-6-methylquinoline is a heterocyclic compound with the molecular formula C10H8BrN. It is a substituted quinoline derivative that features a bromine atom and a methyl group attached to the quinoline ring. Known for its versatile chemical properties, this compound plays a significant role in the field of organic chemistry, particularly as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and as a building block in organic synthesis reactions.
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Used in Pharmaceutical Industry:
3-Bromo-6-methylquinoline is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex molecular structures, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-6-methylquinoline serves as an intermediate in the production of agrochemicals, such as pesticides and herbicides, due to its reactivity and capacity to form stable compounds with biological activity.
Used in Organic Synthesis:
2-Bromo-6-methylquinoline is utilized as a building block in organic synthesis reactions, allowing for the creation of a wide range of organic compounds with diverse applications across various industries, including the development of new materials and chemical products.
First aid Measures of Methylquinoline CAS 302939-86-
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
Quinoline: A Versatile Bioactive Scaffold
Quinolines have become essential to many drugs, including broad-spectrum antibiotics, antivirus, antitubercular, and antimalarial agents. Owing to their importance in medicinal and pharmaceutic industries, several studies have been conducted to synthesize new and novel quinoline derivatives and their hybrid compounds with potent biological applications.
Quinoline is a bicyclic aromatic heterocyclic containing one nitrogen atom. Many natural products as well as marketed drugs contain quinoline moiety. This has earned it an important place in drug discovery. Its nucleus is present in successful antibiotics, anticancer, antivirus, antimalarial, antitubercular, etc, drugs such as Levofloxaxin, Foretinib, Cabozantinib, Neratinib, Saquinavir, Primaquine, Bedaquiline, etc.
In the field of drug discovery, the approach in which two or more pharmacophores are fused as one molecular hybrid in order to have dual or better potency than the individual parents is called hybridization. Drugs containing hybrid molecules have the potential to solve the problems of bioavailability, drug resistance, toxicity, side effect, etc. that are associated with conventional drugs. This superior quality makes hybrid drugs of particular interest to medicinal chemists. Several review articles on synthesis and biological applications of quinoline derivatives have been published.
Chemistry and Coordination Behaviour of Quinolines
Quinoline is an organic heterocyclic compound with a bicyclic structure composed of a benzene ring fused to a pyridine ring. It is a planner and conjugated 10-π electron heterocyclic system. In the form of salts (by easily reacting with acids), it exhibits reactions of benzene as well as pyridine. It contains all sp2 hybridized ring atoms and participates in electrophilic substitution reactions at C-5 and C-8 positions and nucleophilic substitution reactions at C-2 and C-4 positions.
Quinoline-based transition metal complexes as catalysts
The coordination of quinoline ring nitrogen with different transition metals allows quinoline moiety to form stable complexes which can participate as active catalytic species during the diverse organic transformations. The coordination behaviour of quinoline-based complexes with various transition metals prepared for different catalytic applications has been elaborated in this section.
Quinoline-bearing transition metal-based coordination complexes as intermediates in chemical reactions
Quinoline-bearing transition metal-based coordination complexes have emerged as versatile intermediates in a wide variety of chemical reactions, owing to their unique reactivity and ability to undergo diverse transformations. These complexes can act as catalysts, stoichiometric reagents, or as ligands for other metal centres, making them useful tools in synthetic chemistry.
Metal-quinoline coordination complexes in photovoltaics
Quinoline-based complexes have emerged as a promising class of materials for photovoltaic applications due to their unique optoelectronic properties and low-cost synthesis. The unique characteristics of quinoline-based complexes, such as structural properties, electronic properties, ability to form charge-transfer complexes, their tunable absorption and emission properties, etc. make them attractive candidates for their usage in photovoltaic devices.
Biosynce have an independent R&D and inspection center to strictly test the quality of products and provide customers with high quality products, our products are widely exported to North America, Europe, Asia and Africa. We aim to establish long-term and mutually beneficial relationships with customers and offer excellent products and services.

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