1,2,3,4-Tetrahydroacridin-9-amine CAS 321-64-2

1,2,3,4-Tetrahydroacridin-9-amine CAS 321-64-2

CAS No.: 321-64-2
Molecular Formula: C13H14N2
Molecular Weight: 198.26
MDL: MFCD00046923
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Product Introduction

1,2,3,4-Tetrahydroacridin-9-amine CAS 321-64-2 from gram scale to hundreds of kilograms scale. The purity is more than 97%. Our products have good reputation in our industry for their good quality.

 

Chemical Properties

 

Melting point: 182-185 °C

Boiling point: 325.59 °C (rough estimate)

Density: 0.9827 (rough estimate)

Storage conditions: 2-8 °C, way from moisture and light

Appearance: solid

Solubility: Soluble in DMSO (a small amount) and methanol (a small amount)

Enthalpy of Vaporization: 59.9±3.0 kJ/mol

Flash Point: 167.8±27.9 °C

Index of Refraction: 1.682

Molar Refractivity: 59.8±0.5 cm3

 

Synonyms

1,2,3,4-Tetrahydroacridin-9-amine CAS 321-64-2; 1,2,3,4-Tetrahydro-5-aminoacridine; 1,2,3,4-tetrahydro-9-acridinamin; 1,2,3,4-tetrahydro-9-amino-acridin; 1,2,3,4-Tetrahydro-9-aminoacridine; 5-Amino-6,7,8,9-tetrahydroacridine; Acridine,1,2,3,4-tetrahydro-9-amino-; Acridine,9-amino-1,2,3,4-tetrahydro-; Acridine,9-aminotetrahydro-

 

Application

 

1,2,3,4-Tetrahydroacridin-9-amine CAS 321-64-2 is a chemical substance, also known as diethylamine hydroxide. It is an organic amine commonly used in the preparation of chemical products such as deionized water, surfactants, coatings, and dyes.

1,2,3,4-Tetrahydroacridin-9-amine CAS 321-64-2 and its derivatives have potential applications in the treatment of various neurological diseases, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. It has been used in animal models of Alzheimer's disease to investigate its therapeutic potential and the underlying mechanisms of its action. It has also been used as a tool to investigate the role of cholinergic neurotransmission in various cognitive functions in healthy individuals.

 

Safety Information

 

1,2,3,4-Tetrahydroacridin-9-amine CAS 321-64-2 has been found to have hepatotoxicity, which limits its clinical application. Its toxicity is attributed to the formation of a reactive metabolite that can form covalent adducts with cellular biomolecules, leading to cell death. However, its hepatotoxic effects can be reduced by taking antioxidants and other liver protective agents.

 

Attention should be paid to safety during the operation process to protect the health of workers and the safety of the environment.

 

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