Preparation Of Piperidine

It is produced by the catalytic hydrogenation of pyridine. The pyridine and nickel catalyst are added to the autoclave, and hydrogen is added when it is heated to 50 ° C, and the hydrogen is continued to be heated to 200 ° C, and the hydrogen pressure is nearly 7MPa and no longer absorbs hydrogen. The reaction liquid is filtered, the filtrate is fractionated, and the distilled liquid is collected at 102-108℃ to obtain piperidine. Another preparation method is to put pyridine in anhydrous ethanol, heat it, put sodium metal into it, after the reaction is over, use steam distillation to steam piperidine and ethanol, neutralize with hydrochloric acid and steam the ethanol to obtain piperidine hydrochloride, and treat with sodium hydroxide to obtain free piperidine.